Posts Tagged ‘semaglutide’

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Extravagant Wegovy Claims with Limited Evidence at ESC

Extravagant Wegovy Claims with Limited Evidence at ESC

September 2, 2025

Health & Obesity, Scientific Meetings & Publications

It is eye-popping really. Novo Nordisk issued a press release from the European Society of Cardiology (ESC) Congress over the weekend, with extravagant claims for Wegovy versus tirzepatide. Specifically, the claim was that “Wegovy cuts risk of heart attack, stroke or death by 57% compared to tirzepatide.” This is quite an amazing claim to make. […]

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A Striking Contrast in Heart Disease Outcomes at ESC 2025

A Striking Contrast in Heart Disease Outcomes at ESC 2025

September 1, 2025

Health & Obesity, Scientific Meetings & Publications

Researchers presented and published two major studies of heart disease outcomes at the ESC Congress of the European Society of Cardiology over the weekend with strikingly different findings. In the REBOOT study, scientists found that beta blockers have no effect on outcomes when given to patients after a heart attack. None. People might be better […]

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CVS Pharmacy at Night, photograph by Famartin

Ozempic Deal with GoodRx: Compounding and Price Pressure

August 20, 2025

Health & Obesity, Health Policy

By now, it should be obvious. List prices for GLP-1 medicines like semaglutide and tirzepatide are fiction. If you had any doubt, read up on the deal Novo Nordisk just struck with GoodRx to sell both the Ozempic and Wegovy brands of semaglutide for $499 per month. This deal with GoodRx is happening for two […]

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Liver Vaults, photograph by Rodhullandemu

Wegovy Gets the OK from FDA for a MASH Indication

August 16, 2025

Health & Obesity, Health Policy

Late yesterday FDA granted Wegovy (semaglutide 2.4 mg) a big new indication – treatment of MASH. The indication FDA approved reads as follows: “For the treatment of noncirrhotic metabolic dysfunction-associated steatohepatitis (MASH), formerly known as nonalcoholic steatohepatitis (NASH), with moderate to advanced liver fibrosis (consistent with stages F2 to F3 fibrosis) in adults. “The indication […]

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Red Eyes, photograph by Gilles San Martin

New Survey: GLP-1 Awareness Brings New Views of Obesity

August 3, 2025

Consumer Trends, Health & Obesity

YouGov released some fascinating new survey research on Friday that shows GLP-1 awareness rising sharply and a profound shift in views of obesity as this happens. Dramatic Growth in Awareness Two years ago, only 23% of U.S. adults knew “a lot” about semaglutide. Now, that number has grown to 41%. Total awareness is now up […]

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Fading Sun at Castel dell'Ovo, Naples, photograph by Ted Kyle

Compounded Semaglutide Is Slow to Fade Despite FDA

July 30, 2025

Health & Obesity, Health Policy

Monday, Reuters reported that Novo Nordisk has been seeing a bump in prescription volume for Wegovy because FDA had ordered an end to the widespread sale of compounded semaglutide on May 22. New Wegovy prescriptions were up 33%, the report said. But they went on to say that investors were looking for more assurance of […]

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Will Amycretin Lift Novo Nordisk from Its Funk?

Will Amycretin Lift Novo Nordisk from Its Funk?

July 21, 2025

Health & Obesity, Scientific Meetings & Publications

It’s no secret that Novo Nordisk is in something of a funk. In the last year, the value of the company has dropped by half. Its respected leader, Lars Fruergaard Jørgensen, stepped down suddenly in May. Lilly has taken the lead in the obesity market from semaglutide with its own tirzepatide, and numerous competitors are […]

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At Midnight, Light of the Shambhala, painting by Nicholas Roerich

Cardiologists See the Light on Obesity and Heart Failure

July 11, 2025

Health & Obesity, Health Policy, Scientific Meetings & Publications

A new scientific statement from the American College of Cardiology (ACC) marks a milestone in acknowledging the importance of treating obesity in patients with heart failure. It seems that cardiologists see the light and are recognizing the importance of moving beyond diet and lifestyle advice alone. The statement concludes: “Given emerging evidence of the benefits […]

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Landscape with the Fall of Icarus, painting by Pieter Bruegel the Elder

Is Novo Nordisk a Victim of Success or Hubris with Semaglutide?

July 2, 2025

Health & Obesity, Scientific Meetings & Publications

A new report from Reuters tells us that Novo Nordisk is having a hard time coming to terms with its failure to solidify a leadership position in the obesity market it created from nothing with semaglutide. Former executives and financial analysts alike say the company was too conservative and unprepared for a blockbuster launch: “way, way, […]

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Liver Segment Classification by Couinaud, illustration from the Database Center for Life Science and Anatomography BodyParts3D

Obesity Science Fuels a Race for Advances in MASH Therapy

July 1, 2025

Health & Obesity, Scientific Meetings & Publications

A dramatic race is progressing quietly and out of view for most of us. It is the race toward better therapy for the liver disease doctors know as MASH (metabolic associated steatohepatitis), which has close ties to obesity. And likewise because of advances in obesity science, progress in treating MASH is advancing with blinding speed […]

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