Posts Tagged ‘obesity’

A new study in Obesity provides another piece of the puzzle of the influence of PFAS in obesity. PFAS is shorthand for per- and polyfluoroalkyl substances. People also refer to them as “forever chemicals” because they accumulate in our environment and our bodies. The new study tells us that PFAS exposure in teens having metabolic […]

Late yesterday FDA granted Wegovy (semaglutide 2.4 mg) a big new indication – treatment of MASH. The indication FDA approved reads as follows: “For the treatment of noncirrhotic metabolic dysfunction-associated steatohepatitis (MASH), formerly known as nonalcoholic steatohepatitis (NASH), with moderate to advanced liver fibrosis (consistent with stages F2 to F3 fibrosis) in adults. “The indication […]

Yesterday the Canadian Medical Association Journal and Obesity Canada published new clinical guidance for obesity medicines – a leap forward that reflects great clinical progress in pharmacotherapy. This is the second revision to the chapter on pharmacotherapy since the Canadian guideline for adult obesity care was first published in 2020. The chapter was also updated […]

Here’s something to ponder. Floating in the North Atlantic, there are more metric tons of nanoplastics than the combined mass of all mammals living on dry land. That’s a lot. This observation comes from a recent study in the journal Nature. Unfortunately, we cannot be certain of the impact of this ubiquitous pollution on human […]

Sisyphus, the myth of a person condemned to a futile task of rolling a boulder uphill for eternity, has long been an apt metaphor for obesity medicine. He still is, said Donna Ryan yesterday at the Louisiana 2025 Obesity Conference in New Orleans. But the narrative has shifted dramatically, she explained. Before this shift, the […]

This is a painful lesson and most of the world is very slow to take it to heart. Dealing with obesity – on almost every level – is a marathon, not a sprint. Today’s lesson is about orforglipron, an oral GLP-1 agonist in development by Lilly. This drug is a small molecule that can be […]

At the opening of the ANZMOSS (Australian and New Zealand Metabolic and Obesity Surgery Society) meeting today, we had the unique privilege of helping people peer into the future of obesity care. Endocrine surgeon Juan Pablo Pantoja presented a view of the future of bariatric surgery in the era of a medical frenzy. The frenzy, […]

We have a great privilege this week to spend time in Canberra (and Sydney), delivering two invited presentations and finally meeting up with quite a number of people we have known only virtually. Now in person. The occasion is the annual meeting of ANZMOSS – the Australian and New Zealand Metabolic and Obesity Surgery Society. […]

A new study yesterday in Nature Medicine will surely add fuel to the fire of people who believe we can simply blame ultra-processed foods for the rise in obesity over the last four decades. The design of the study was solid – a randomized controlled crossover study. Just the kind of thing that sticklers for […]

After the strong and subjective opinions we keep hearing about the uselessness of BMI, it is refreshing to see a careful analysis of objective data. A new study in Annals of Family Medicine suggests measuring percent body fat through bioimpedance is superior for predicting mortality linked to excess adiposity. Bioimpedance is the method seca and […]